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Resources

Evidence-based insights from our clinical team

Papers

Abstract: Ketamine in Psychiatric Treatment:  An Evidence-Based Clinical Overview

By Alexander Papp, MD and Julie Myers, PsyD

A clinical overview covering ketamine's mechanism of action, indications, treatment protocols, and safety considerations, with links to the supporting research.

Check back soon for more!

Blog: Reflections on Psychiatry & Psychology

Our blog posts share our briefer clinical perspectives. 

Ketamine Articles

Acute Antidepressant Effects Of Intramuscular Versus Intravenous Ketamine​​​​

Indian Journal of Psychological Medicine – 2014

 

The 'Ketamine And Me' Project - A qualitative study of patients’ experience of ketamine treatment for depression​

​Journal of Affective Disorders Reports – 2021

 

Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression​​​

Psychotherapy and Psychosomatics – 2017

 

GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions

Journal of Clinical Investigations - 2020

 

Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder ​​​

JAMA Psychiatry – 2014

 

Ketamine Assisted Psychotherapy (KAP): Patient Demographics, Clinical Data and Outcomes in Three Large Practices Administering Ketamine with Psychotherapy

Journal of Psychoactive Drugs – 2019

 

Ketamine Treatment For Depression: Opportunities For Clinical Innovation And Ethical Foresight​

The Lancet Psychiatry – 2017

 

Replication of Ketamine’s Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial​​

Biological Psychiatry – 2012

 

Long-Term Maintenance With Intramuscular Ketamine for Treatment-Resistant Bipolar II Depression​​

American Journal of Psychiatry – 2012

 

Safety And Efficacy Of Maintenance Ketamine Treatment In Patients With Treatment-refractory Generalised Anxiety And Social Anxiety Disorders​​

Journal of Psychopharmacology – 2018

 

Side-effects Associated With Ketamine Use In Depression: A Systematic Review​

The Lancet Psychiatry – 2018

 

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression​

Biological Psychiatry – 2012

What Is The Mechanism Of Ketamine’s Rapid-onset Antidepressant Effect? A Concise Overview Of The Surprisingly Large Number Of Possibilities​​​​​​

​Journal of Clinical Pharmacy and Therapeutics – 2017

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