top of page
Sunrays-transp.png
Waves-transp.png

Resources

Evidence-based insights from our clinical team

Brief Posts & Papers 

Reflections on Psychiatry & Psychology 

Our blog posts share our briefer clinical perspectives. 

By Alexander Papp, MD and Julie Myers, PsyD

​

A clinical overview covering ketamine's mechanism of action, indications, treatment protocols, and safety considerations, with links to the supporting research.

And overview of the research findings on brain zaps from discontinuation of antidepressant medications. 

Articles on Ketamine

Acute Antidepressant Effects Of Intramuscular Versus Intravenous Ketamine​​​​

​Indian Journal of Psychological Medicine – 2014

 

The 'Ketamine And Me' Project - A qualitative study of patients’ experience of ketamine treatment for depression​

​Journal of Affective Disorders Reports – 2021

 

Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression​​​

Psychotherapy and Psychosomatics – 2017

 

GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions

Journal of Clinical Investigations - 2020

 

Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder â€‹â€‹â€‹

JAMA Psychiatry – 2014

 

Ketamine Assisted Psychotherapy (KAP): Patient Demographics, Clinical Data and Outcomes in Three Large Practices Administering Ketamine with Psychotherapy

Journal of Psychoactive Drugs – 2019

 

Ketamine Treatment For Depression: Opportunities For Clinical Innovation And Ethical Foresight​

The Lancet Psychiatry – 2017

 

Replication of Ketamine’s Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial​​

Biological Psychiatry – 2012

 

Long-Term Maintenance With Intramuscular Ketamine for Treatment-Resistant Bipolar II Depression​​

American Journal of Psychiatry – 2012

 

Safety And Efficacy Of Maintenance Ketamine Treatment In Patients With Treatment-refractory Generalised Anxiety And Social Anxiety Disorders​​

Journal of Psychopharmacology – 2018

 

Side-effects Associated With Ketamine Use In Depression: A Systematic Review​

The Lancet Psychiatry – 2018

 

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression​

Biological Psychiatry – 2012

​

What Is The Mechanism Of Ketamine’s Rapid-onset Antidepressant Effect? A Concise Overview Of The Surprisingly Large Number Of Possibilities​​​​​​

​Journal of Clinical Pharmacy and Therapeutics – 2017

bottom of page