A large Cochrane review of 67 randomized trials (>2,300 patients) found no clear evidence that ketamine or other NMDA-receptor antagonists reduce chronic non-cancer pain. Evidence quality was rated low to very low, so current data do not reliably support ketamine as an effective pain treatment.
Biofeedback teaches control over body functions. HRV biofeedback helps sync heart rate and breathing, boosting parasympathetic response, improving stress, anxiety, and self-regulation.
