Reflections on Psychiatry & Psychology

A large Cochrane review of 67 randomized trials (>2,300 patients) found no clear evidence that ketamine or other NMDA-receptor antagonists reduce chronic non-cancer pain. Evidence quality was rated low to very low, so current data do not reliably support ketamine as an effective pain treatment.

The lateral habenula (LHb) stands out as a critical structure in understanding depression. This blog explores the LHb's role in the intricate landscape of neuroscience, its connection to depressive symptoms, and how ketamine therapy offers new hope by affecting this brain structure. The Lateral Habenula: A Critical Brain Structure The lateral habenula (LHb) is a small, symmetrical, paired nucleus located deep within the brain, nestled between the two thalamic bodies. It is in

There are several exciting developments in the field of antidepressants, with various drugs currently in the pipeline. still in various stages of development. Clinical trials are ongoing to evaluate their safety, effectiveness, and potential side effects.

Lavender, used since antiquity, may ease anxiety. Its compounds (linalool, linalyl acetate) act on serotonin and NMDA receptors. Silexan (Calm-Aid) is a studied extract; consult your doctor due to potential drug interactions.