Reflections on Psychiatry & Psychology

Prescription nutraceuticals sometimes used in psychiatry include Deplin and EnLyte (L-methylfolate formulations that support neurotransmitter production) and Vascepa and Lovaza (omega-3 fatty acids). They are not antidepressants but may be added to treatment to support mood and overall brain health.

Methylfolate, the active form of folate (B9), supports serotonin and dopamine production and may help depression, especially in people with MTHFR variants or treatment-resistant cases. It can cause GI upset or insomnia and should be used cautiously, especially with SSRIs, under medical supervision.