Reflections on Psychiatry & Psychology

Ketamine and postpartum depression: A landmark BMJ study found that a single dose of esketamine after childbirth reduced postpartum depression by 75% in at-risk mothers. Learn what this means for prenatal depression treatment and maternal mental health.

Psychedelic psychiatry is moving from fringe research to mainstream clinical practice. An overview of psilocybin, MDMA, and ketamine — including benefits, risks, and what the evidence supports.

The lateral habenula (LHb) stands out as a critical structure in understanding depression. This blog explores the LHb's role in the intricate landscape of neuroscience, its connection to depressive symptoms, and how ketamine therapy offers new hope by affecting this brain structure. The Lateral Habenula: A Critical Brain Structure The lateral habenula (LHb) is a small, symmetrical, paired nucleus located deep within the brain, nestled between the two thalamic bodies. It is in

Zurzuvae, the first FDA-approved oral pill for postpartum depression, is taken for 14 days and can reduce symptoms within days. Costing about $15,900, access may be limited despite its rapid action compared with traditional antidepressants.

Zuranolone (Zurzuvae) is the first oral GABA-modulating antidepressant for postpartum depression. Taken for 14 days, it can improve symptoms within 3 days; benefits may last weeks. Common side effects include drowsiness and dizziness.

Biofeedback teaches control over body functions. HRV biofeedback helps sync heart rate and breathing, boosting parasympathetic response, improving stress, anxiety, and self-regulation.

Bipolar II disorder alternates between depression and hypomania but is hard to diagnose because patients often enjoy or fail to recognize hypomania and seek help only during depression. Recollections may be distorted, so collateral history from others is often crucial for accurate diagnosis.

Research shows a two-way gut–brain link: gut bacteria shape brain development and influence mood. Dysbiosis may contribute to anxiety and depression. Probiotics show mental health benefits, but aren’t yet FDA-regulated or reliable stand-alone treatments.